Mechanisms in pulmonary toxicology.
نویسنده
چکیده
Specific accumulation and biotransformation of drugs cause cell injury in the lung. Evoked mechanisms are oxidative injury, direct cytotoxic effects, intracellular deposition of phospholipids, and immune reaction. Individual susceptibility can be due to genetically determined metabolic idiosyncrasy or to immune-mediated hypersensitivity.
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عنوان ژورنال:
- Clinics in chest medicine
دوره 25 1 شماره
صفحات -
تاریخ انتشار 2004